Alterations in transforming growth factor (TGF)- signalling have been frequently implicated in human cancer, and an important mechanism underlying its pro-oncogenic nature is suppression of the host antitumour immune response. or recombinant TGF- but only after administration of CFA. In addition, host cyclooxygenase-2 and kinin receptors played an important role in the induction of TGF–mediated… Continue reading Alterations in transforming growth factor (TGF)- signalling have been frequently implicated