Some therapeutic monoclonal antibodies function by focusing the killing power of the immune system on particular mobile targets, an activity referred to as antibody-dependent cell-mediated cytotoxicity (ADCC). system of action referred to as antibody-dependent cell-mediated cytotoxicity (ADCC). [1] In cases like this, the Fc area (Fig. 1) of specific antibody isotypes can recruit effector substances… Continue reading Some therapeutic monoclonal antibodies function by focusing the killing power of