Microsomal prostaglandin E synthase-1 (mPGES-1) is an inducible enzyme that specifically catalyzes the conversion of prostaglandin (PG)H2 to PGE2. and PGE2-dependent phenotypic changes of non-hematopoietic/mesenchymal stromal cells play a key role in T-cell dependent humoral immune responses by formation of germinal centers and interactions with mesenchymal stromal cells (35, 36). To characterize the functional significance… Continue reading Microsomal prostaglandin E synthase-1 (mPGES-1) is an inducible enzyme that specifically