Hamsters are widely used to generate monoclonal antibodies against mouse, rat, and human antigens, but sequence and structural information for hamster immunoglobulins is sparse. HL4E10 is the first example of a hamster lambda light chain and only the second known GW3965 HCl complete hamster heavy chain sequence. The crystal structure of the HL4E10 Fab at… Continue reading Hamsters are widely used to generate monoclonal antibodies against mouse, rat,
Category: Low-density Lipoprotein Receptors
Because of the different mechanisms HIV-1 has evolved to escape from
Because of the different mechanisms HIV-1 has evolved to escape from a neutralizing antibody response it has been extremely challenging to develop an effective anti-HIV-1 vaccine. in the neutralization of tier 1 and a representative tier 2 clade B computer virus suggesting the constrained V3 peptide immunogen correctly mimics the V3 conformation actually in tier… Continue reading Because of the different mechanisms HIV-1 has evolved to escape from